IRRADIATION AND BRAIN-TUMORS IN RATS

Authors
MORIN M ALLIN F ALTMEYER S MASSE R
Citation
M. Morin et al., IRRADIATION AND BRAIN-TUMORS IN RATS, Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie, 317(3), 1994, pp. 277-281
Citations number
22
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie → ACNP
ISSN journal
07644469
Volume
317
Issue
3
Year of publication
1994
Pages
277 - 281
Database
ISI
SICI code
0764-4469(1994)317:3<277:IABIR>2.0.ZU;2-S
Abstract
Sprague-Dawley rats were exposed to Co 60 irradiation (3 Gy) at differ ent ages. Rats were distributed among sham-control (618 males and 120 females) and exposed groups: foetus (66 males and 65 females), 3 month -old (304 males), and 9 month-old (120 males and 60 females). The inci dence of brain tumours war 5.3 % in male control rats and nil in femal e control rats. Brain tumour incidence decreased in 3 month-old rats ( 3.3 %), and increased from 6.6 % in 3 month-old rats to 15.2 % in male foetuses and 12.3 % in female foetuses. Age at incidence of brain tum ours decreased in irradiatiated animals. Astrocytomas were the more su sceptible type of brain tumours to radiocarcinogenesis.