L. Davidsson et al., BIOAVAILABILITY IN INFANTS OF IRON FROM INFANT CEREALS - EFFECT OF DEPHYTINIZATION, The American journal of clinical nutrition, 65(4), 1997, pp. 916-920
Iron bioavailability from an infant cereal made of wheat flour with a
low extraction rate (70%) and cow milk was measured in infants by usin
g a stable-isotope technique. A dephytinized infant cereal was prepare
d by adding commercial phytase during manufacture, resulting in degrad
ation of 88% of the native phytic acid. Paired comparisons were made t
o evaluate the effect of phytic acid on iron bioavailability. Both inf
ant cereals contained identical amounts of ascorbic acid and had a mol
ar ratio of ascorbic acid to iron of 2:1. Iron was added as ferrous su
lfate. No difference in iron bioavailability was observed in this stud
y; the geometric mean was 8.7% (range: 3.8-16.9%) and 8.5% (range: 3.4
-21.4%) from the cereal with native phytic acid (0.08% phytic acid) an
d the dephytinized cereal (0.01% phytic acid), respectively. Dephytini
zation of infant cereals containing a relatively low native phytic aci
d content and high amounts of ascorbic acid is thus unnecessary to ens
ure adequate bioavailability of iron.