The effects of hostility on bilateral measures of skin conductance dur
ing affective facial configurations were investigated. Highly hostile
and non-hostile men were instructed in making facial configurations th
at were identified by raters as happy, angry, or neutral. Subjects wer
e asked to make the set of facial configurations twice with unstructur
ed baselines taken prior to each expression. Significant increases in
skin conductance were found from baseline across all three facial conf
igurations. Skin conductance varied as a function of affect, decreasin
g from angry to happy to neutral configurations. A three-way group x h
and x block interaction was found. The high-hostile group showed persi
stence in the elevation of conductance at the left hand through Block
2. In contrast, reduced skin conductance at the left hand was found in
the low-hostile group, along with habituation at the left hand across
blocks. The possibility of altered right cerebral systems in high-hos
tile individuals is discussed.