INFLUENCE OF THE N-MOM GROUP IN THE ENANTIOSELECTIVE LIPASE-CATALYZEDMETHANOLYSIS OF RACEMIC 1,4-DIHYDROPYRIDINE DICARBOXYLATES

Authors
DECASTRO MS SALAZAR L SINISTERRA JV
Citation
Ms. Decastro et al., INFLUENCE OF THE N-MOM GROUP IN THE ENANTIOSELECTIVE LIPASE-CATALYZEDMETHANOLYSIS OF RACEMIC 1,4-DIHYDROPYRIDINE DICARBOXYLATES, Tetrahedron : asymmetry, 8(6), 1997, pp. 857-858
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
6
Year of publication
1997
Pages
857 - 858
Database
ISI
SICI code
0957-4166(1997)8:6<857:IOTNGI>2.0.ZU;2-R
Abstract
The hydrolysis of l-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylates, N -methoxymethylated and N-unsubstituted has been. carried out using lip ases AK and PS from Pseudomonas. The presence of N-MOM changed the ena ntiopreference of lipase AK but not of lipase PS. The observed enantio preference of the lipases is not changed by the nature of the organic solvent or the temperature. (C) 1997 Elsevier Science Ltd.