Ovuplant(TM) (Fort Dodge Laboratories, Fort Dodge, IA) is a subcutane
ous implant for the short-term release of 2.1 mg of the potent GnRH an
alog deslorelin. When used in estral mares with a lead follicle > 30 m
m in diameter, ovulation occurs within 48 hours in most mares. In this
study, Ovuplant was used strategically on two Thoroughbred farms with
three stallions to space breedings close to ovulations and by this to
conserve the breeding use of the stallions in 47 mares receiving 51 t
reatments; 67 untreated mares served as contemporary controls. Treatme
nt resulted in ovulations within 48 hours in 94.1% of the mares, with
a mean interval to ovulation of 42.4 hours (range: 24 to 96 hours). Tr
eatment reduced the number of breedings per estrus and far the entire
season to 1.16 and 1.36 per mare vs. 1.40 and 3.58 in untreated contro
ls (P < 0.05), and the number of estrus periods for the season (1.17 v
s. 2.57; P < 0.05). Early pregnancy rates for treated and untreated ma
res were 68.2% vs. 64.1% at the treatment estrus, or a contemporary es
trus in controls. Early pregnancy rates from breedings at two subseque
nt estrous periods were 88.6 and 82.8% for treated and untreated mares
, respectively.