E. Vangeffen et al., OPERATIVE MANAGEMENT OF IMPENDING PATHOLOGICAL FRACTURES - A CRITICALANALYSIS OF THERAPY, Journal of surgical oncology, 64(3), 1997, pp. 190-194
Background: Evident and impending pathological fractures should be sta
bilised operatively because patients are in serious pain and debilitat
ed for their remaining life span. Methods: We evaluated survival and f
unctional results after operative therapy. A retrospective study was c
onducted concerning 116 patients with 152 impending pathological fract
ures. Results: Of all operated patients, postoperatively 79% regained
walking capacity and 60% required no or only occasional analgesic drug
s. Patients operated on for impending pathological fractures showed be
tter functional results, as well as those operated with the additional
use of polymethylmethacrylate (PMMA). Prophylactic use of antibiotics
reduced the number of infectious complications significantly. The med
ian survival after operative therapy was 15 months. Conclusions: We co
nclude that impending pathological fractures should be operatively sta
bilised, if possible, with the additional use of PMMA because of bette
r functional results. (C) 1997 Wiley-Liss, Inc.