THE GABA(A) RECEPTOR ALPHA(6) SUBUNIT GENE (GABRA6) IS TIGHTLY LINKEDTO THE ALPHA(1)-GAMMA(2) SUBUNIT CLUSTER ON MOUSE CHROMOSOME-11

Authors
GARRETT KM HAQUE D BERRY D NIEKRASZ I GAN JP ROTTER A SEALE TW
Citation
Km. Garrett et al., THE GABA(A) RECEPTOR ALPHA(6) SUBUNIT GENE (GABRA6) IS TIGHTLY LINKEDTO THE ALPHA(1)-GAMMA(2) SUBUNIT CLUSTER ON MOUSE CHROMOSOME-11, Molecular brain research, 45(1), 1997, pp. 133-137
Citations number
47
Categorie Soggetti
Neurosciences
Journal title
Molecular brain research → ACNP
ISSN journal
0169328X
Volume
45
Issue
1
Year of publication
1997
Pages
133 - 137
Database
ISI
SICI code
0169-328X(1997)45:1<133:TGRASG>2.0.ZU;2-W
Abstract
We have established that the GABA(A) receptor alpha(6) (Gabra6) and al pha(1) (Gabra1) subunit genes are tightly linked on mouse chromosome 1 1 by analyzing the strain distribution patterns of RFLPs for the two g enes and microsatellite markers flanking these genes in 26 BXD recombi nant inbred strains. These results further demonstrate clustering of t he GABA(A) receptor subunit genes on mouse chromosomes and the synteny for these clusters between the mouse and human genomes.