RISK OF CANCER IN MIGRANTS AND THEIR DESCENDANTS IN ISRAEL .1. LEUKEMIAS AND LYMPHOMAS

Cancer registrations among young individuals (under age 30 years) for the 30-year period 1960-1989 were used to investigate the risk of leuk aemia and lymphoma in migrants to Israel, and in their offspring, rela tive to Israel-born individuals with Israel-born parents. Relative ris ks by the father's continent of origin, and odds ratios by continent o f origin of mother or both parents, adjusted for age, sex and period, were estimated. The leukaemias showed little variation in risk by birt hplace, and no change between generations. For non-Hodgkin lymphoma, h owever, there were quite large differences in incidence, with relative ly high rates in migrants from Asia and Africa These persisted to some degree into the second generation, suggesting that inherited suscepti bility may underlie some of the variation. (C) 1997 Wiley-Liss, Inc.