ASYMMETRIC CATALYTIC INTRAMOLECULAR HYDROACYLATION OF 4-SUBSTITUTED PENT-4-ENALS TO BETA-SUBSTITUTED CYCLOPENTANONES

Authors
BARNHART RW MCMORRAN DA BOSNICH B
Citation
Rw. Barnhart et al., ASYMMETRIC CATALYTIC INTRAMOLECULAR HYDROACYLATION OF 4-SUBSTITUTED PENT-4-ENALS TO BETA-SUBSTITUTED CYCLOPENTANONES, Chemical communications, (6), 1997, pp. 589-590
Citations number
27
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
6
Year of publication
1997
Pages
589 - 590
Database
ISI
SICI code
1359-7345(1997):6<589:ACIHO4>2.0.ZU;2-P
Abstract
The catalyst, [Rh(S,S-Me-duphos)(acetone)(2)](+), rapidly and efficien tly converts 4-substituted pent-4-enals bearing primary and secondary substituents to the corresponding cyclopentanones and for a variety of substituents the ee was found to range from 93 to 96% at 25 degrees C .