AZAFLUORENES - SYNTHESIS AND TRANSFORMATI ONS

Citation
Ns. Prostakov et al., AZAFLUORENES - SYNTHESIS AND TRANSFORMATI ONS, Uspehi himii, 66(2), 1997, pp. 131-150
Citations number
199
Categorie Soggetti
Chemistry
Journal title
ISSN journal
00421308
Volume
66
Issue
2
Year of publication
1997
Pages
131 - 150
Database
ISI
SICI code
0042-1308(1997)66:2<131:A-SATO>2.0.ZU;2-2
Abstract
Data on the chemistry of azafluorenes (indenopyridines) over the past 20 years are surveyed. Methods for the synthesis of azafluorene isomer s with the nitrogen atom in all the possible positions are considered. The main reactions of azafluorenes are analysed. Their reactivity is determined by the presence and mutual influence of the two fused rings of different natures (benzene and pyridine rings) as well as by the o rder of conjugation of benzene and pyridine fragments. The main transf ormations of substituents occupying various positions of the azafluore ne system are considered. Data on the natural occurrence of azafluoren es, biological activities of their derivatives, and on the structure a nd physicochemical properties of azafluorenes and their derivatives ar e presented.