STRUCTURE OF HBP, A MULTIFUNCTIONAL PROTEIN WITH A SERINE PROTEINASE FOLD

Authors
IVERSEN LF KASTRUP JS BJORN SE RASMUSSEN PB WIBERG FC FLODGAARD HJ LARSEN IK
Citation
Lf. Iversen et al., STRUCTURE OF HBP, A MULTIFUNCTIONAL PROTEIN WITH A SERINE PROTEINASE FOLD, Nature structural biology, 4(4), 1997, pp. 265-268
Citations number
22
Categorie Soggetti
Biology,"Cell Biology
Journal title
Nature structural biology → ACNP
ISSN journal
10728368
Volume
4
Issue
4
Year of publication
1997
Pages
265 - 268
Database
ISI
SICI code
1072-8368(1997)4:4<265:SOHAMP>2.0.ZU;2-4
Abstract
The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional pro tein with antibacterial activity, monocyte and T-cell activating prope rties and endotoxin and heparin binding capacity.