SENSITIVITY OF AEROMONAS-HYDROPHILA CARBAPENEMASE TO DELTA(3)-CEPHEMS- COMPARATIVE-STUDY WITH OTHER METALLO-BETA-LACTAMASES

Authors
FELICI A PERILLI M FRANCESCHINI N ROSSOLINI GM GALLENI M FRERE JM ORATORE A AMICOSANTE G
Citation
A. Felici et al., SENSITIVITY OF AEROMONAS-HYDROPHILA CARBAPENEMASE TO DELTA(3)-CEPHEMS- COMPARATIVE-STUDY WITH OTHER METALLO-BETA-LACTAMASES, Antimicrobial agents and chemotherapy, 41(4), 1997, pp. 866-868
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
41
Issue
4
Year of publication
1997
Pages
866 - 868
Database
ISI
SICI code
0066-4804(1997)41:4<866:SOACTD>2.0.ZU;2-T
Abstract
Ceftriaxone and ceftriaxone S-oxide behaved as inactivators against th e metallo beta-lactamase of Aeromonas hydrophila AE036 and as substrat es for the zinc beta-lactamase produced by Bacillus cereus (569/H/9) a nd Stenotrophomonas maltophilia ULA 511. Moreover, RO 09-1428, a catec hol-cephalosporin, was not recognized by the A. hydrophila enzyme. Pan ipenem, cephalosporin C, cephalosporin C-gamma-lactone, and loracarbef were substrates for the three studied beta-lactamases.