E. Gouaux, THE LONG AND SHORT OF COLICIN ACTION - THE MOLECULAR-BASIS FOR THE BIOLOGICAL-ACTIVITY OF CHANNEL-FORMING COLICINS, Structure, 5(3), 1997, pp. 313-317
Channel-forming colicins undergo a remarkable series of conformational
gyrations during their voyage from the extracellular milieu to the pe
riplasmic membrane, Crystal structures of the intact colicin la molecu
le and a channel-forming domain of colicin El illuminate relationships
between the molecular structure and biological function of these volt
age-dependent channel-forming toxins.