IDENTIFICATION OF PROJECTIONS FROM THE CENTRAL NUCLEUS OF THE AMYGDALA TO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS WHICH ARE IMMUNOREACTIVE FOR CORTICOTROPIN-RELEASING HORMONE IN THE RAT
A. Marcilhac et P. Siaud, IDENTIFICATION OF PROJECTIONS FROM THE CENTRAL NUCLEUS OF THE AMYGDALA TO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS WHICH ARE IMMUNOREACTIVE FOR CORTICOTROPIN-RELEASING HORMONE IN THE RAT, Experimental physiology, 82(2), 1997, pp. 273-281
Corticotrophin-releasing hormone (CRH) immunoreactivity was detected i
n neurons of the central nucleus of the amygdala that were retrogradel
y labelled by injection of a fluorescent tracer (True Blue) into the p
araventricular nucleus of the hypothalamus (PVN). The double-labelled
neurons were located mainly in the medial subdivision of the central n
ucleus and appeared to comprise less than one-fifth of the descending
pathway. These results suggest that CRH may act as a neurotransmitter
in the amygdalo-hypothalamic pathway.