Bl. Gruber et al., ISOLATED PULMONARY MICROANGIITIS MIMICKING PNEUMONIA IN A PATIENT INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS, Journal of rheumatology, 24(4), 1997, pp. 759-762
We describe the first case, to our knowledge, of apparently isolated p
ulmonary vasculitis mimicking bacterial pneumonia in a patient infecte
d with human immunodeficiency virus (HIV). Patients presenting with fe
ver, cough, and pulmonary infiltrates present a diagnostic challenge.
As a result of severe T cell mediated immunosuppression and humoral dy
sregulation, the differential diagnosis is diverse. One must consider
both noninfectious and infectious etiologies. Noninfectious etiologies
such as pulmonary lymphoma, endobronchial Kaposi's sarcoma, and adver
se drug reactions are common. Recent recognition of the paradoxical as
sociation between HIV and systemic vasculitis requires additional ackn
owledgment of this problem in diagnosis.