Objectives-After an inquiry from the employees of an offset printing p
lant, a historical cohort study was conducted to investigate cancer mo
rtality among these workers. Methods-The cohort comprised 262 men, who
contributed 2771 person-years of observation. 16 deaths were identifi
ed during the follow up period (1980-91). Expected numbers of deaths w
ere derived from age specific regional rates. Standardised mortality r
atios (SMR) and 95% confidence intervals (95% CIs) were calculated. Re
sults-An increased cancer mortality was found after 10 years of employ
ment (SMR 213, 95% CI 98 to 405, based on nine deaths), mainly due to
a high mortality from lung cancer (SMR 381, 95% CI 104 to 975, four de
aths), and from oesophageal cancer (SMR 1049, 95% CI 216 to 3065, thre
e deaths). For workers with at least 20 years since the start of emplo
yment, the SMR was 262 (95% CI 105 to 540) for all cancer sites, 447 (
95% CI 92 to 1306) for lung cancer, and 1094 (95% CI 132 to 3952) for
oesophageal cancer. The increased cancer mortality was concentrated am
ong pressmen. Conclusion-Although based on small numbers, the findings
suggest an increased risk of cancer among these workers, which should
be further investigated.