Activated Protein C resistance is a recently described clotting disord
er, accounting for several previously undiagnosed thrombophilic states
, Initially this defect had been associated with leg vein thromboses,
but it is now recognised that other vascular beds are also prone to cl
otting in this disorder. We report a case of acute proptosis in a pati
ent,vith Activated Protein C resistance, due to cavernous sinus thromb
osis.