DIPOLE LOCALIZATION IN PATIENTS WITH EPILEPSY USING THE REALISTICALLYSHAPED HEAD MODEL

Dipole sources were localized in 3 patients with epilepsy using both t he realistically shaped head model and the 3-sphere model. Interictal spikes were recorded from 63 closely spaced scalp electrodes. The scal p, skull, and brain surfaces were digitized from a MRI of each patient 's head, and each surface was tessellated by 1600 triangles. Single di pole fits to the EEG were performed using both the realistically shape d head model and the 3-sphere model. The 2 models localized dipoles to positions that differed from one another by 1-3 cm. For dipoles local ized to the temporal lobe, the most important difference between model s was that the realistically shaped head model localized the dipole lo wer in the brain than the 3-sphere model. The realistically shaped hea d model was more in accordance with the ECoG findings than the 3-spher e model. (C) 1997 Elsevier Science Ireland Ltd.