CELLULAR IMMUNO-COMPETENCE OF INFECTED ROOT-CANAL CONTENTS IN PATHOGENESIS OF PERIAPICAL LESIONS

Authors
NINOMIYA J NAKANISHI K TAKEMOTO T HIGASHI T OGAWA T KAWAGUCHI H YOSHINO H HIRAKAWA M SHIBA H HINO F SHIBATA K HINO T
Citation
J. Ninomiya et al., CELLULAR IMMUNO-COMPETENCE OF INFECTED ROOT-CANAL CONTENTS IN PATHOGENESIS OF PERIAPICAL LESIONS, Journal of endodontics, 23(4), 1997, pp. 213-216
Citations number
20
Categorie Soggetti
Dentistry,Oral Surgery & Medicine
Journal title
Journal of endodontics → ACNP
ISSN journal
00992399
Volume
23
Issue
4
Year of publication
1997
Pages
213 - 216
Database
ISI
SICI code
0099-2399(1997)23:4<213:CIOIRC>2.0.ZU;2-V
Abstract
The soluble fractions of infected root canal contents (IRCC) were coll ected from about 300 human extracted teeth and examined for the presen ce of mononuclear cell (MNC) chemotaxis and cellular immunocompetence. IRCC showed remarkable chemotactic activity for polymorphonuclear leu kocytes but a weak activity for MNC. However, generation of intrinsic MNC chemotaxis and induction of cellular immunity were confirmed in ra ts given repeated injections of IRCC.