A HEPATIC GRAFT TUBERCULOSIS TRANSMITTED FROM A LIVING-RELATED DONOR

Exclusion of occult diseases in the donor organ and prevention of infe ctious disease transmission are minimal requirements in organ transpla ntation. We report here a case of hepatic graft tuberculosis, which wa s most likely transmitted by the graft from the living-related donor. The course of the recipient included tuberculosis, rejection, and othe r infections, which led to vanishing bile duct syndrome. Due to variou s infections and tuberculosis, as well as a strong interaction between rifampicin and tacrolimus, the patient died of pneumonia on day 273 a fter transplantation. This case emphasizes the importance of care in t he selection of a living-related donor for liver transplantation.