PREPARATION AND INTRAMOLECULAR RADICAL CYCLIZATION OF SOME CYCLIC N-SULFONYLENAMINES

Authors
AHMAN J SOMFAI P
Citation
J. Ahman et P. Somfai, PREPARATION AND INTRAMOLECULAR RADICAL CYCLIZATION OF SOME CYCLIC N-SULFONYLENAMINES, Journal of the Chemical Society. Perkin transactions. I, (8), 1994, pp. 1079-1082
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
8
Year of publication
1994
Pages
1079 - 1082
Database
ISI
SICI code
0300-922X(1994):8<1079:PAIRCO>2.0.ZU;2-D
Abstract
Cyclic N-sulfonylenamines can be prepared under mild conditions from t he corresponding lactams by an efficient two-step procedure involving diisobutylaluminium hydride (DIBAL) or LiAIH(4) reduction followed by CF3CO2H induced dehydration. In addition, appropriately substituted N- sulfonylenamines are substrates in intramolecular radical cyclizations . forming the corresponding spirocyclic sulfonamides in good yields.