ANTI-RNP ANTIBODY IN A CHILD WITH UNDIFFERENTIATED CARCINOMA AND NO EVIDENCE OF MIXED CONNECTIVE-TISSUE DISEASE

Authors
FOSTER HE MALLESON PN PETTY RE CABRAL DA
Citation
He. Foster et al., ANTI-RNP ANTIBODY IN A CHILD WITH UNDIFFERENTIATED CARCINOMA AND NO EVIDENCE OF MIXED CONNECTIVE-TISSUE DISEASE, British journal of rheumatology, 36(2), 1997, pp. 289-291
Citations number
16
Categorie Soggetti
Rheumatology
Journal title
British journal of rheumatology → ACNP
ISSN journal
02637103
Volume
36
Issue
2
Year of publication
1997
Pages
289 - 291
Database
ISI
SICI code
0263-7103(1997)36:2<289:AAIACW>2.0.ZU;2-9
Abstract
We describe a young girl who presented with musculoskeletal symptoms a nd who was found to have high titres of antinuclear antibody with anti -RNP antibody. She was initially suspected of having mixed connective tissue disease, but ultimately was found to have metastatic undifferen tiated carcinoma with an unknown primary site. This is a very uncommon malignancy of childhood and an association with anti-RNP antibody has , to our knowledge, not been described. The clinical significance of t his finding is discussed.