a rare case of mixed connective tissue disease (MCTD) with acute polyr
adiculoneuropathy is reported, A 23-year-old woman presented with high
body temperature, arthralgia and a headache, and developed gait distu
rbance two weeks later, She had many clinical features common to patie
nts with MCTD. Her neurological manifestations were diagnosed as acute
polyradiculoneuropathy based on the clinical picture, combined with s
upportive ancillary data, including cerebrospinal fluid (CSF) analysis
, electrophysiological evaluation, sural nerve biopsy, peroneus brevis
muscle biopsy, and magnetic resonance imaging (MRI), Her neurologic d
eficits, as well as associated laboratory findings, were improved by c
orticosteroid therapy.