FLOW-INJECTION SPECTROPHOTOMETRIC DETERMINATION OF FRUSEMIDE OR SULFATHIAZOLE IN PHARMACEUTICALS

Authors
GARCIA MS SANCHEZPEDRENO C ALBERO MI RODENAS V
Citation
Ms. Garcia et al., FLOW-INJECTION SPECTROPHOTOMETRIC DETERMINATION OF FRUSEMIDE OR SULFATHIAZOLE IN PHARMACEUTICALS, Journal of pharmaceutical and biomedical analysis, 15(4), 1997, pp. 453-459
Citations number
42
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Journal of pharmaceutical and biomedical analysis → ACNP
ISSN journal
07317085
Volume
15
Issue
4
Year of publication
1997
Pages
453 - 459
Database
ISI
SICI code
0731-7085(1997)15:4<453:FSDOFO>2.0.ZU;2-W
Abstract
Two sensitive and fast flow-injection spectrophotometric methods are p roposed for the determination of frusemide or sulphathiazole based on the formation of coloured complexes between these compounds and Pd(II) at pH 5.0 and 55 degrees C. Using the peak height as a quantitative p arameter, frusemide or sulphathiazole was determined at 410 nm over th e range 2.0 x 10(-5)-4.0 x 10(-4) M or 5.0 x 10(-5)-3 x 10(-4) M, resp ectively. The methods were applied to the determination of these sulph onamides in pharmaceuticals.