EFFECT OF LONG-TERM ANGIOTENSIN-CONVERTING ENZYME-INHIBITION ON VASCULAR FUNCTION IN PATIENTS WITH CHRONIC CONGESTIVE-HEART-FAILURE

Authors
JESERICH M PAPE L JUST H HORNIG B KUPFER M MUNZEL T LOHMANN A OLSCHEWSKI M DREXLER H
Citation
M. Jeserich et al., EFFECT OF LONG-TERM ANGIOTENSIN-CONVERTING ENZYME-INHIBITION ON VASCULAR FUNCTION IN PATIENTS WITH CHRONIC CONGESTIVE-HEART-FAILURE, The American journal of cardiology, 76(14), 1995, pp. 1079
Citations number
19
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
76
Issue
14
Year of publication
1995
Database
ISI
SICI code
0002-9149(1995)76:14<1079:EOLAEO>2.0.ZU;2-U
Abstract
We demonstrate that peripheral vasodilatory capacity is impaired in pa tients with chronic congestive heart failure not treated with aspirin, but preserved in patients taking aspirin. Chronic angiotensin-convert ing enzyme inhibition improves the decreased vasodilatory capacity in these patients, indicating that locally acting cyclooxygenase-dependen t factors contribute to peripheral vasoconstriction in chronic congest ive heart failure.