In vivo adsorption of salivary proteins onto prosthetic titanium compo
nents was analyzed after exposure of titanium abutments to the oral en
vironment for a period of 2 to 6 weeks. Gel electrophoresis and Wester
n immunoblotting were used to separate and identify the proteins, whic
h were mainly cu-amylase and serum albumin. Selective adsorption of pr
oteins enables attachment of specific oral bacteria and thus may alter
the composition of the dental plaque formed on titanium surfaces.