INFANTILE OSTEOPETROSIS - BONE-MARROW TRANSPLANTATION FROM A COUSIN DONOR

Authors
TAYLOR GM DEARDEN SP WILL AM EVANS DIK STEVENS RF SIMON S SUPER M MORRELL G FERGUSSON WD BROWN IH
Citation
Gm. Taylor et al., INFANTILE OSTEOPETROSIS - BONE-MARROW TRANSPLANTATION FROM A COUSIN DONOR, Archives of Disease in Childhood, 73(5), 1995, pp. 453-455
Citations number
9
Categorie Soggetti
Pediatrics
Journal title
Archives of Disease in Childhood → ACNP
ISSN journal
00039888
Volume
73
Issue
5
Year of publication
1995
Pages
453 - 455
Database
ISI
SICI code
0003-9888(1995)73:5<453:IO-BTF>2.0.ZU;2-N
Abstract
The successful correction of infantile osteopetrosis in an Asian child by bone marrow transplantation (BMT) from an HLA-A,B matched cousin d onor is reported. Retrospective HLA molecular analysis revealed-that p atient and donor were incompatible for HLA-DPB1. Donor type cells dete cted in the patient after transplantation indicate successful engraftm ent. The patient is currently alive and well.