Em. Merkle et al., FUROSEMIDE UROGRAM IN PATIENTS WITH NEOBL ADDER, RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 165(5), 1996, pp. 480-483
To differentiate between urodynamically relevant obstruction and funct
ionally unimportant dilation of the upper urinary tract in patients wi
th neobladder using a modified furosemide urogram. Method: An excretor
y urogram with furosemide loading was carried out in 19 patients with
neobladder and sonographically and urographically confirmed dilation o
f the upper urinary tract. Once strong contrasting of the renal pelves
and calyces has been achieved, 20 mg of furosemide were applied and l
ate radiographs were obtained at 15 min and 30 min, respectively. An o
bstruction was defined as increasing dilation of the renal pelves and
calices during forced diuresis and lack of washout effect of the contr
ast medium. Results: In 32 cases, the renoureteral unit (RUU) was dila
ted on ultrasound. Of these, 25 RUU's showed good emptyness of contras
t medium upon stimulation of diuresis, six RUU's returned a borderline
findings, while one RUU was found to exhibit a decompensated anastomo
tic stenosis, which was dilated. Two further patients with borderline
findings were later treated surgically due to their pain symptoms. No
patient required further preoperative diagostic procedures. Conclusion
s: The modified furosemide urogram represents a cost-effective diagnos
tic orientation strategy in patients with neobladder and dilated renal
pelves and calyces and is both well-tolerated by patients and meets w
ith broad acceptance from the urologic staff.