The state of resting sleep is associated with a series of oscillations
generated in cortical and thalamic networks. A newly discovered rhyth
m groups the spindle and delta sleep oscillations within slowly recurr
ing (<1Hz) sequences. Multi-site, extra- and intracellular recordings
provide evidence for synchronization of various classes of cell in the
neocortex and thalamus during sleep oscillations that might reach par
axysmal levels similar to epileptic states. Sleep oscillations and the
underlying synchronizing processes are disrupted during transition to
brain arousal.