Bl. Eppley et Am. Sadove, RESORBABLE COUPLING FIXATION IN CRANIOSYNOSTOSIS SURGERY - EXPERIMENTAL AND CLINICAL-APPLICATIONS, The Journal of craniofacial surgery, 6(6), 1995, pp. 477-482
The use of resorbable bone fixation devices composed of a copolymer of
polyglycolic acid and polylactic acid were investigated in an animal
model as well as in human application. We used resorbable plates and m
etallic microscrews in immature rabbits; plating of the coronal suture
resulted in complete device resorption and increased interscrew dista
nces (i.e., growth across the suture) after 8 postoperative months. In
20 infants with calvarial deformities, thin, straight resorbable plat
es were used for skeletal fixation after osteotomies and repositioning
. A total of 231 fixation devices were implanted without complications
after 12 postoperative months. These encouraging results have led to
further clinical application in craniosynostosis deformities.