Defects resulting after resection of malignant tumors of the paranasal
sinuses ii involving the anterior base of the skull need an adequate
closure. In addition to such avital tissue as fascia lata, fat,or cera
mics, in recent years we used free muscle flaps from the latissimus do
rsi for reconstruction. We performed this reconstructive method in sev
en patients after radical tumor resection. The operation was performed
in cooperation with the neurosurgeon. In three cases a transfrontal i
n combination with a transfacial approach was used and in four cases o
nly a transfacial approach was chosen. The flap was tailored as a pure
muscle transplant if only the base of the skull had to be repaired an
d the surgical cavity had to be obliterated. In three cases a skin pad
dle was left on the muscle to perform a closure of the orbit and the h
ard palate. In four patients we performed primary reconstruction, in t
hree cases secondary reconstruction, which was necessary because cereb
rospinal fluid (CSI;) leakage occurred after primary reconstruction wi
th avital tissue in addition to insufficient pericranial flap. None of
the patients with primary reconstruction developed CSF leakage. There
was no free flap failure. The aim of this reconstruction is a safe cl
osure of skull base defects to prevent infection, meningitis, brain ab
scess, and brain herniation.