A SIMPLE ROUTE TO SYN ALPHA-AMINO-BETA-HYDROXY ESTERS BY C-2 REGIOSELECTIVE OPENING OF ALPHA,BETA-EPOXY ESTERS WITH METAL-HALIDES

Authors
RIGHI G RUMBOLDT G BONINI C
Citation
G. Righi et al., A SIMPLE ROUTE TO SYN ALPHA-AMINO-BETA-HYDROXY ESTERS BY C-2 REGIOSELECTIVE OPENING OF ALPHA,BETA-EPOXY ESTERS WITH METAL-HALIDES, Tetrahedron, 51(48), 1995, pp. 13401-13408
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
48
Year of publication
1995
Pages
13401 - 13408
Database
ISI
SICI code
0040-4020(1995)51:48<13401:ASRTSA>2.0.ZU;2-R
Abstract
alpha,beta-Epoxy esters are opened by NaX (X = I, Br) in a regio and s tereoselective fashion to beta-hydroxy-alpha-halo esters, which repres ent suitable precursors of syn alpha-amino-beta-hydroxy esters and bet a-hydroxy esters.