The literature on the incentives for R&D cooperation with spillovers t
ypically deals only with the factors affecting cooperative profits. Th
is paper focuses on the incentives to cheat and the stability of such
cooperative agreements in a repeated game framework. It is shown that
the stability of cooperation is influenced by the nature and magnitude
of spillovers, relative to the nature and degree of product market co
mpetition. While cooperative profits are higher with large positive (e
xogenous, unintended) know-how spillovers, such as in fundamental rese
arch, our analysis shows that it may be easier to sustain cooperation
in areas with lower spillovers, such as applied research, because of t
he smaller incentives to cheat on the initial agreement, at feast when
firms produce substitutes. Alternatively, the possibility of technolo
gy sharing (i.e., intended or endogenous spillovers), besides R&D coor
dination, not only increases cooperative profits but also reduces the
incentives to defect from a cooperative equilibrium.