PROCESSING AND ACTIVATION OF RECOMBINANT MOUSE MASTOCYTOMA HISTIDINE-DECARBOXYLASE IN THE PARTICULATE FRACTION OF SF9 CELLS BY PORCINE PANCREATIC ELASTASE

Authors
TANAKA S FUKUI T YAMAMOTO J SHIMA Y KUME T OHGO M ICHIKAWA A
Citation
S. Tanaka et al., PROCESSING AND ACTIVATION OF RECOMBINANT MOUSE MASTOCYTOMA HISTIDINE-DECARBOXYLASE IN THE PARTICULATE FRACTION OF SF9 CELLS BY PORCINE PANCREATIC ELASTASE, Biochimica et biophysica acta. Protein structure and molecular enzymology, 1253(1), 1995, pp. 9-12
Citations number
18
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Protein structure and molecular enzymology → ACNP
ISSN journal
01674838
Volume
1253
Issue
1
Year of publication
1995
Pages
9 - 12
Database
ISI
SICI code
0167-4838(1995)1253:1<9:PAAORM>2.0.ZU;2-G
Abstract
Mature 53 kDa histidine decarboxylase (HDC) peptide is produced from a precursor 74 kDa peptide. The mechanism of specific cleavage by proce ssing enzyme is unknown. Using the recombinant mouse 74 kDa HDC, we fo und that porcine pancreatic elastase specifically converted the inacti ve 74 kDa HDC to its active form of 53 kDa HDC.