NORMOLIPEMIC PLANE XANTHOMATOSIS, PARAPRO TEINEMIA, ANTI-LIPOPROTEIN ACTIVITY, COMPLEMENT ABNORMALITIES

Introduction. Normolipaemic plane xanthomatosis is classically associa ted with a monoclonal gammapathy. Case report. We observed this associ ation in a 69-year-old woman. This case was particular since anti-lipo protein activity due to a monoclonal IgG immunoglobulin was found in t he serum with abnormal complement fractions. The paraproteinaemia rema ined stable after a 2-year follow-up. Conclusion. This association is remarkable. The anti-lipoprotein activity of the monoclonal protein sh ould be emphasized in light of the immunological processes involved in the pathogenesis of this association.