S. Candy et al., THE VALUE OF AN ELIMINATION DIET IN THE MANAGEMENT OF PATIENTS WITH ULCERATIVE-COLITIS, South African medical journal, 85(11), 1995, pp. 1176-1179
Debate exists about the role of diet in both the aetiology and the man
agement of ulcerative colitis, To examine the latter, a group of patie
nts with documented ulcerative colitis was studied at the Groote Schuu
r Hospital Gastrointestinal Clinic. A total of 18 subjects, 9 female a
nd 9 male, were randomised into active or control groups and followed
up weekly for 6 weeks, Subjects in the control group were asked to doc
ument but not alter their intake of food and drink, Those in the exper
imental group had their diets systematically manipulated to exclude fo
ods that appeared to provoke symptoms, The symptoms, sigmoidoscopy and
biopsy findings of all subjects were compared before and after, 'Remi
ssion' was defined as the passage of normal stools with absence of rec
tal bleeding, 'Improvement' was defined as a decrease in the number of
diarrhoeal stools and/or a diminution of rectal bleeding. At the end
of the trial the diet group displayed significantly fewer symptoms tha
n did the controls (p = 0,009; Fisher's exact test), Sigmoidoscopic fi
ndings improved in 8 subjects in the diet group compared with 2 of the
controls, Histological findings improved in 3 of the diet group as we
ll as in 3 of the controls. There were no foods that provoked symptoms
in all patients, though spiced and curried foods and fruits, especial
ly grapes, melon and the citruses, commonly caused diarrhoea. In only
2 patients were symptoms reproduced consistently on reintroduction of
a particular food, pork in 1 case and yellow cheese in another.