Fj. Gamo et al., THE LOW-AFFINITY COMPONENT OF THE GLUCOSE-TRANSPORT SYSTEM IN SACCHAROMYCES-CEREVISIAE IS NOT DUE TO PASSIVE DIFFUSION, Yeast, 11(14), 1995, pp. 1393-1398
It has been claimed that the low-affinity component of glucose transpo
rt in Saccharomyces cerevisiae is due to passive diffusion of the suga
r across the plasma membrane. We have investigated this possibility. F
or this purpose we have measured the permeability coefficient of hexos
es in this organism. We have found that this coefficient is at least t
wo to three orders of magnitude lower than required to account for the
low-affinity component of glucose transport, and have concluded that
this component is not due to passive diffusion.