Bl. Thompson et al., CONGENITAL-SYPHILIS IN MARYLAND, 1989-1991 - THE EFFECT OF CHANGING THE CASE-DEFINITION AND OPPORTUNITIES FOR PREVENTION, Sexually transmitted diseases, 22(6), 1995, pp. 364-369
Background: The reported incidence of congenital syphilis in the Unite
d States rose dramatically during the 1980s. Although lack of prenatal
care has been associated with congenital syphilis, little has been pu
blished regarding missed opportunities for prenatal intervention. Goal
of this Study: To determine whether congenital syphilis increases in
Maryland between 1989 and 1991 resulted from a true increase in congen
ital syphilis incidence or a change in the surveillance case definitio
n, and to describe missed opportunities for prenatal intervention. Stu
dy Design: This was a retrospective cohort study. Results: When the re
vised case definition was used, a 473% increase in the number of cases
was seen. Among infants who met the revised definition, 45% of mother
s had received no prenatal care. Among those whose mothers had receive
d prenatal care, opportunities to intervene were missed for 53%. Concl
usions: Although a true increase in congenital syphilis incidence occu
rred before 1990, the increase reported in Maryland between 1989 and 1
991 was primarily due to the change in case definition. Many cases of
congenital syphilis could have been prevented with early and adequate
prenatal care.