This is a case report of a 35-year-old woman infected with the human i
mmunodeficiency virus who presented with acute bacterial sepsis that p
roved to be secondary to Neisseria gonorrhoeae. Typical skin and joint
findings developed only after the acute sepsis had resolved. Patients
with disseminated gonococcal infection rarely have signs of acute bac
terial sepsis. This case raises the question of whether HIV-infected p
atients are at an increased risk of contracting severe gonococcal dise
ase.