SYNTHESIS OF A MORPHINE-6-GLUCURONIDE HAPTEN, N-(4-AMINOBUTYL)NORMORPHINE-6-GLUCURONID AND RELATED HAPTENS

Authors
BROWN RT CARTER NE LUMBARD KW SCHEINMANN F
Citation
Rt. Brown et al., SYNTHESIS OF A MORPHINE-6-GLUCURONIDE HAPTEN, N-(4-AMINOBUTYL)NORMORPHINE-6-GLUCURONID AND RELATED HAPTENS, Tetrahedron letters, 36(47), 1995, pp. 8661-8664
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
47
Year of publication
1995
Pages
8661 - 8664
Database
ISI
SICI code
0040-4039(1995)36:47<8661:SOAMHN>2.0.ZU;2-X
Abstract
For use as a hapten in the radioimmunoassay of morphine-6-glucuronide 2 (M6G), N-(4-aminobutyl)normorphine-6-glucuronide 12 has been prepare d, together with related haptens, using the imidate coupling method de veloped for synthesis of M6G; a rebuttal of recent critical comments o n our synthesis of M6G is included.