The purified lipophorin of Aedes aegypti (Diptera) is composed of two
apolipoproteins: apolipophorin I(M(r) = 224,000) and apolipophorin II
(M(r) = 73,000). The density of lipophorin is constant during the Aede
s life-cycle and equal to 1.11 +/- 0.01 g/ml. The amount of lipophorin
per animal, during the gonotrophic cycles, increases until 48 hr afte
r blood-feeding and then decreases until there is a new blood intake.
The density values and quantification of lipophorin during Aedes aegyp
ti gonotrophic cycle suggest that the adaptation to a higher lipid tra
nsport demand during oogenesis in Aedes aegypti is accomplished by inc
reasing the amount of lipophorin in the hemolymph. This response is di
fferent from that observed in Musca domestica (Diptera) that does not
involve changes in hemolymph lipophorin levels.