EVOLUTIONARY COMPUTATION FOR REVEAL STRUC TURE-ACTIVITY-RELATIONSHIPSIN 3-PHENOXYCHROMONE AND 3-PHENOXY-4-HYDROXYCOUMARIN DERIVATIVES

Authors
TETKO IV TANCHUK VY VASILEV SA KHILYA VP PODA GI LUIK AI
Citation
Iv. Tetko et al., EVOLUTIONARY COMPUTATION FOR REVEAL STRUC TURE-ACTIVITY-RELATIONSHIPSIN 3-PHENOXYCHROMONE AND 3-PHENOXY-4-HYDROXYCOUMARIN DERIVATIVES, Bioorganiceskaa himia, 21(10), 1995, pp. 809-815
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
21
Issue
10
Year of publication
1995
Pages
809 - 815
Database
ISI
SICI code
0132-3423(1995)21:10<809:ECFRST>2.0.ZU;2-U
Abstract
Based on a set of compounds possessing hypolipidemic activity, it was demonstrated that evolutionary algorithms can be successfully used to compile an informative set of molecular parameters. The parameter sets selected using the method of potential functions allowed correct pred iction of the activity of test molecules.