CONTRIBUTION OF SPECIFIC CELL-ADHESIVE GLYCOPROTEINS TO AIRWAY AND ALVEOLAR INFLAMMATION AND DYSFUNCTION

Authors
CHURCHILL L GUNDEL RH LETTS LG WEGNER CD
Citation
L. Churchill et al., CONTRIBUTION OF SPECIFIC CELL-ADHESIVE GLYCOPROTEINS TO AIRWAY AND ALVEOLAR INFLAMMATION AND DYSFUNCTION, The American review of respiratory disease, 148(6), 1993, pp. 83-87
Citations number
32
Categorie Soggetti
Respiratory System
Journal title
The American review of respiratory disease → ACNP
ISSN journal
00030805
Volume
148
Issue
6
Year of publication
1993
Supplement
S
Pages
83 - 87
Database
ISI
SICI code
0003-0805(1993)148:6<83:COSCGT>2.0.ZU;2-#
Abstract
Using various animal models of toxic or antigenic-induced airway infla mmation, we have demonstrated that adhesion molecules play an importan t role in the recruitment, retention, and site-specific activation of inflammatory cells within the airways. Furthermore, we have shown that cytokines may contribute to inflammatory responses in the airways by enhancing the expression of adhesion molecules on respiratory epitheli al cells.