CEREBROSPINAL-FLUID EXAMINATION IN A CASE OF CHILDHOOD ORBITAL GRANULOCYTIC SARCOMA

The diagnosis of a case of childhood orbital granulocytic sarcoma, ini tially classified as a poorly-differentiate malignant tumor, was final ly considered at the time of relapse following primary treatment with chemotherapy and local irradiation. At this time, systematic cerebrosp inal fluid examination showed numerous blast cells with Auer rods, con sistent with the diagnosis of meningeal acute myeloid leukemia of M2 t ype, and concomitant biopsy of the tumor indicated the diagnosis of ch loroma. Reevaluation of the primary biopsy confirmed this diagnosis. ( C) 1996 Wiley-Liss, Inc.