Kh. Koo et al., PREVENTING COLLAPSE IN EARLY OSTEONECROSIS OF THE FEMORAL-HEAD - A RANDOMIZED CLINICAL-TRIAL OF CORE DECOMPRESSION, Journal of bone and joint surgery. British volume, 77B(6), 1995, pp. 870-874
We performed a randomised trial on 37 hips (33 patients) with early-st
age osteonecrosis (ON). After the initial clinical evaluation, includi
ng plain radiography and MRI, 18 hips were randomly assigned to a core
-decompression group and 19 to a conservatively-treated group. All the
patients were regularly followed up by clinical evaluation, plain rad
iography and MRI at intervals of three months. Hip pain was relieved i
n nine out of ten initially symptomatic hips in the core-decompression
group but persisted in three out of four initially painful hips in th
e conservatively-treated group at the second assessment (p < 0.05). At
a minimum follow-up of 24 months, 14 of the 18 core-decompressed hips
(78%) and 15 of the 19 non-operated hips (79%) developed collapse of
the femoral head. By survival analysis, there was no significant diffe
rence in the time to collapse between the two groups (log-rank test p
= 0.79). Core decompression may be effective in symptomatic relief, bu
t is of no greater value than conservative management in preventing co
llapse in early osteonecrosis of the femoral head.