STRUCTURAL AND CONFORMATIONAL-ANALYSIS OF NATURALLY-OCCURRING CULARINE N-OXIDE ALKALOIDS

Authors
SUAU R SEGURA RG SILVA MV VALPUESTA M
Citation
R. Suau et al., STRUCTURAL AND CONFORMATIONAL-ANALYSIS OF NATURALLY-OCCURRING CULARINE N-OXIDE ALKALOIDS, Heterocycles, 41(11), 1995, pp. 2575-2585
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
41
Issue
11
Year of publication
1995
Pages
2575 - 2585
Database
ISI
SICI code
0385-5414(1995)41:11<2575:SACONC>2.0.ZU;2-V
Abstract
(+)-cis- and (+)-trans-Cularidine N-oxides were isolated from Ceratoca pnos heterocarpa. Their structures and conformations were derived from H-1, C-13, one dimensional nOe nmr data and their chemical behaviour. The trans isomer possesses the usual conformation of cularine alkaloi ds and readily undergoes Cope elimination. The cis isomer exhibits a d ifferent conformation at the dihydroxepine ring.