FAST SOLUTE RELEASE FROM PHOTOSENSITIVE LIPOSOMES - AN ALTERNATIVE TOCAGED REAGENTS FOR USE IN BIOLOGICAL-SYSTEMS

Authors
MORGAN CG BISBY RH JOHNSON SA MITCHELL AC
Citation
Cg. Morgan et al., FAST SOLUTE RELEASE FROM PHOTOSENSITIVE LIPOSOMES - AN ALTERNATIVE TOCAGED REAGENTS FOR USE IN BIOLOGICAL-SYSTEMS, FEBS letters, 375(1-2), 1995, pp. 113-116
Citations number
15
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
375
Issue
1-2
Year of publication
1995
Pages
113 - 116
Database
ISI
SICI code
0014-5793(1995)375:1-2<113:FSRFPL>2.0.ZU;2-A
Abstract
The kinetics of release of soluble marker trapped in liposomes of gel phase phospholipid containing a photoisomerisable phospholipid analogu e have been investigated, Marker release is triggered by UV laser flas h photolysis at 355 nm, A markedly temperature-dependent release rate is seen, and above 25 degrees C millisecond release kinetics can be ac hieved, These results suggest that such liposomes might find applicati on as an alternative to conventional 'caged' reagents for photo-trigge red reagent release in biological research.