Purpose: Calf muscle pump dysfunction is a recognized factor in chroni
c venous insufficiency (CVI). We investigated the hypothesis that limb
s with CVI have a reduced ankle range of motion (ROM) that may be resp
onsible for the poor calf pump function associated with venous ulcerat
ion. Methods: Ankle ROM and calf pump function were assessed in 32 lim
bs of 26 adult men. Limbs were selected on the basis of clinical prese
ntation: normal (n = 6 limbs), class 1 or 2 CVI with no history of ulc
eration (n = 9 Limbs), class 3 CVI with healed ulceration (n = 9 limbs
), and class 3 CVI with active ulceration (n = 8 limbs). ROM was deter
mined by goniometry during maximal plantar flexion and dorsiflexion of
the ankle. Calf pump function was determined by air plethysmographic
measurement of ejection fraction (EF) and residual volume fraction (RV
F). Results: Ankle ROM was significantly (P < 0.05) reduced in each CV
I: group compared with age-matched control subjects, because of decrea
ses in both plantar flexion and dorsiflexion. Calf pump function was s
ignificantly impaired (decreased EF and increased RVF) in ulcerated li
mbs. ROM was significantly correlated to EF and RVP. Impairment of ROM
and calf pump function was associated with deterioration in the clini
cal classification of venous disease. Conclusions: Limbs with CVI have
a limited ankle ROM that decreases with increasing severity of clinic
al symptoms. This decreased ROM is associated with, and may contribute
to, poor calf pump function.