The history, clinical and histological features and response to treatm
ent of a 15-year-old horse with cutaneous lymphoma are described. The
mare had an 11 year history of multiple cutaneous nodules. A diagnosis
of cutaneous lymphoma was made on histological examination of biopsy
material taken on two separate occasions some 4 years apart. Subsequen
t immunohistochemical staining identified the cell lineage as T-lympho
cytes. This is the first report of immunophenotypic characterisation o
f cutaneous lymphoma in the horse. The horse was treated with intrales
ional glucocorticoids and oral progestins, and complete resolution of
the nodules resulted.