Areas of increased echogenicity in the fetal abdomen are defined as ab
normally bright areas with an echogenicity similar to that of surround
ing bones. Such areas are encountered in various normal and abnormal p
rocesses. When increased echogenicity is discovered in the fetal abdom
en, a careful search should be made for a potential cause. The causes
to be considered depend on the location of the areas of increased echo
genicity, which can be classified as intestinal, peritoneal, hepatic,
retroperitoneal, and parietal. In each case, vascular, ischemic, infec
tious, tumoral, metabolic, and chromosomal abnormalities should be inc
luded in the differential diagnosis before considering the finding a n
ormal variant. Therefore, in utero detection of fetal abdominal areas
of increased echogenicity requires a complete sonographic survey of th
e fetus and placenta along with close sonographic follow-up, evaluatio
n of familial factors, and testing for possible associated cystic fibr
osis, infection, or a chromosomal anomaly. The prognosis depends more
on the underlying disease than on the extent of the increased echogeni
city.